Pharmacology Diabetes Meds

Glucotrol
What is the *trade/brand name* for Glipizide?

Glipizide
What is the *generic name* for Glucotrol?

Oral Hypoglycemic
What *class of drug* is Glucotrol/Glipizide?

Glucotrol/Glipizide
This drug is indicated as an:
● Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Glucotrol/Glipizide (*Board question*)
This medication can cause: *Board question*
● Low blood sugar (hypoglycemia) which may occur if you do not consume enough calories (from food, juices, fruit, etc.)
● Easy bruising or bleeding

Glucophage/Glucophage XR
What is the *trade/brand name* for Metformin Hcl?

Metformin Hcl
What is the *generic name* for Glucophage/Glucophage XR?

Oral Hypoglycemic
What *class of drug* is Glucophage/Glucophage XR/Metformin Hcl?

Glucophage/Glucophage XR/Metformin Hcl
This drug is indicated as an:
● Adjunct to diet and exercise to improve glycemic control in adults and children with type 2 diabetes mellitus.

Glucophage/Glucophage XR/Metformin Hcl
This medication can cause:
● Low blood sugar (hypoglycemia)
● Lactic acidosis

Bydureon/Byetta(injection)
What is the *trade/brand name* for
Exenatide?

Exenatide
What is the *generic name* for Bydureon/Byetta(injection)?

Hypoglycemic
What *class of drug* is Bydureon/Byetta(injection)/Exenatide?

Bydureon/Byetta(injection)/Exenatide
This subcutaneous injection/drug is indicated as an:
● Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
● Not a substitute for insulin

Bydureon/Byetta(injection)/Exenatide
This medication can cause:
● Low blood sugar
● Swelling/weight gain
● Feeling short of breath
● Urinating less than usual or not at all

Bydureon/Byetta(injection)/Exenatide
Antibiotics and birth control pills should be taken at least 1 hr before this medicine as it will decrease effectiveness if taken together.

Actos
What is the *trade/brand name* for Pioglitazone Hydrochloride?

Pioglitazone Hydrochloride
What is the *generic name* for Actos?

Oral Anti-Diabetic Medication
What *class of drug* is Actos/Pioglitazone Hydrochloride?

Actos/Pioglitazone Hydrochloride
This drug is indicated as an:
● Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus in multiple clinical settings
● Not be used to treat type 1 diabetes or diabetic ketoacidosis
● Exerts its antihyperglycemic effect only in the presence of endogenous insulin

Actos/Pioglitazone Hydrochloride (*Board question*)
This medication can cause: *Board question*
● Swelling or rapid weight gain
● Painful urination
● Stomach pain, blood in your urine

Amaryl
What is the *trade/brand name* for Glimepiride?

Glimepiride
What is the *generic name* for Amaryl?

Hypoglycemic Agent
What *class of drug* is Amaryl/Glimepiride?

Amaryl/Glimepiride
This drug is indicated as an:
● Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
● Not be used for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis

Amaryl/Glimepiride
This medication can cause:
● Low Blood Sugar
● Severe skin rash, itching, redness, or irritation
● Pale skin, easy bruising or bleeding

Novolin R
What is the *trade/brand name* for Human Insulin?

Human Insulin
What is the *generic name* for Novolin R?

Insulin
What *class of drug* is Novolin R/Human Insulin?

Novolin R/Human Insulin
This injection/drug is indicated to:
● Improve glycemic control in adults and children with diabetes mellitus.

Novolin R/Human Insulin
This medication can cause:
● Hypoglycemia (low blood sugar)*
● Injection Site reactions*
● headache
● hunger
● weakness
● sweating
● tremors
● irritability

Novolin R/Human Insulin
This injection/drug is a human zinc suspension insulin that is an intermediate-acting insulin that starts to work more slowly but lasts longer than regular insulin.

Humulin 70/30
What is the *trade/brand name* for Insulin Human Isoprene Suspension?

Insulin Human Isoprene Suspension
What is the *generic name* for Humulin 70/30?

Insulin
What *class of drug* is Humulin 70/30/Insulin Human Isoprene Suspension?

Humulin 70/30/Insulin Human Isoprene Suspension
This injection/drug is indicated to:
● Improve glycemic control in adult patients with diabetes mellitus.

Humulin 70/30/Insulin Human Isoprene Suspension
This medication can cause:
● Blurred vision
● Diziness
● Drowsiness due to low/high blood sugar levels

Humulin 70/30/Insulin Human Isoprene Suspension
This drug is a fixed ratio premix recombinant human insulin formulation with a mixture of 70% intermediate-acting insulin (isoprene) and 30% short-acting insulin (regular) & starts to work as quickly as regular insulin but lasts longer.

Synthroid
What is the *trade/brand name* for Levothyroxine Sodium?

Levothyroxine Sodium
What is the *generic name* for Synthroid?

Thyroid Hormone/Gland
What *class of drug* is Synthroid/Levothyroxine Sodium?

Synthroid
*Board question*
● If taken it can cause increased energy & metabolism
● If not taken it will cause decreased energy & metabolism.

Synthroid/Levothyroxine Sodium
This injection/drug is indicated:
● As replacement or supplemental therapy in congenital or acquired *hypothyroidism*
● Pituitary TSH Suppression
● In the treatment or prevention of various types of euthyroid goiters
● Thyroid nodules
● Hashimoto’s thyroiditis
● Multi nodular goiter
● As an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer

Synthroid/Levothyroxine Sodium
This medication can cause:
● headache
● sleep problems (insomnia)
● feeling nervous or irritable
● fever, hot flashes, sweating

Tapazole
What is the *trade/brand name* for Methimazole?

Methimazole
What is the *generic name* for Tapazole?

Antithyroid Agent
What *class of drug* is Tapazole/Methimazole?

Tapazole/Methimazole
This tablet/drug is indicated:
● In patients with Graves’ disease with hyperthyroidism or toxic multinodular goiter for whom surgery or radioactive iodine therapy is not an appropriate treatment option
● To ameliorate symptoms of hyperthyroidism in preparation for thyroidectomy or radioactive iodine therapy

Tapazole/Methimazole
This medication can cause:
● Stomach upset
● Nausea
● Vomiting
● Loss of taste
● Headache
● Joint/Muscle pain
● Abnormal hair loss
● Drowsiness
● Dizziness
● Burning/tingling of hands/feet

Glipizide and Metformin (Metaglip) (*Board question*)
Two drugs that can be a combined type of insulin *Board question*

U-100 (100 units of insulin per mL)/U-500 (500 units of insulin per mL) (*Board question*)
How are insulin doses measured? (for adults) *Board question*

Insulin (*Board question*)
● Has to be injected because the body will break it down if it is ingested.
● Will also give the best results if injected in the same general area *Board question*

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