The most common form of Parkinsonism is PD. The result of the loss of dopamine-producing brain cells is primary symptoms mentioned above. PD is called as primary Parkinsonism or idiopathic Parkinson’s disease. A term mentioning a disorder for which there is no cause has been found is described condition idiopathic. The cause of PD is known or suspected in other form of PD. PD is a neurodegenerative brain disorder which progresses very slowly in many people in worldwide.
A production of neurotransmitter called dopamine is stop by person’s brain. Therefore insufficient amount of dopamine present in brain. Due to the less amount of dopamine present in brain, person loss ability to regulate the body movements, body and emotions. There are serious complications from the disease. The complications from PD are rated as the 14th top cause of death in the United States by Centers for Disease Control and Prevention (CDC).
No total cure is there for PD. Dopamine is normally produced by brain cells known as neurons in the human brain. Substantia nigra is particular area of the brain where these neurons are concentrating. Dopamine is a chemical that relays messages between the substantia nigra and other parts of the brain to control movements of the human body. The smooth, coordinated muscle movements in human body are due to dopamine. The motor symptoms of Parkinson’s disease appear when approximately 60 to 80% of the dopamine-producing cells are damaged, and do not produce enough dopamine, This process of impairment of brain cells is called neuro degeneration.
The enteric nervous system, the medulla and in particular, the olfactory bulb, which controls your sense of smell involves earliest signs of Parkinson’s, which is current theory called as Braak’s hypothesis. The theory explains that over the years PD only to the substantia nigra and cortex. For classify the degree of pathology in Parkinson’s disease and Alzheimer’s disease Braak staging refers to two methods. By performing an autopsy of the brain clinical diagnosis of these diseases obtained. For detection of PD as early as possible researchers are mainly worked on these “non-motor” symptoms. Person might hear his doctor refer to his Hoehn and Yahr stage. This scale, first introduced in 1967, is a simple rating tool used by clinicians as a means to generally describe how motor symptoms progress in Parkinson’s. It takes into account factors other than motor symptoms, including mental functioning, mood and social interaction.
While symptoms are unique to each person, and the progression of symptoms varies from person to person, knowing the typical stages of Parkinson’s can help you cope with changes as they occur. In some people, it could take 20 years to go through these stages. In others, the disease progresses more quickly.