Antigen Based Vaccines for Cancer Treatment


Download PDF

I would recommend using the Antigen based vaccines for your cancer treatment. Antigen based vaccines contain purified tumor proteins which are known as antigens. Those antigens are injected to stimulate the patient’s antigen presenting cells to take up the antigen and present it to T cells. A T cell is a type of white blood cell that is key to an immune system. The T cell is a part of a system that tailors the bodies immune response to specific pathogens. The use of this therapy is to find a specific type of antigen for any particular type of cancer. Usually these tumor vaccine therapies are only effective in cancer types that have well defined tumor antigens. I have to let you know that a huge struggle with vaccine cancer treatments is the problem identifying tumor specific antigens.

Antigen Vaccines are the only cancer treatment to overcome the peripheral immune tolerance and elicit a non toxic immune response. A non toxic immune response is when antigens are substances on the surface of cells,viruses,fungi, or bacteria. Non living substances such as toxins,chemicals,drugs,and foreign particles can also be antigens. Your immune system learns to see these antigens as normal and usually does not react against them. Cancer based vaccines are meant to be used to help treat cancer that has already developed. Most vaccines are used to help stop cancer cell growth or to slow the cell down as well as to create tumor shrinkage, to prevent cancer from coming back, and to kill cancer cells that have not been killed by other treatment.

Cancer treatment vaccines are suppose to activate the T cells which are located in the thymus. (www.cancer.gov)Once these T cells are activated they are meant to be redirected to recognize specific types of cancer. When they recognize this cancer they make antibodies which bind to molecules on the surface of a cancer cell. After this vaccines with antigens are injected into the body. When these antigens are released into the body they create an immune response which causes the T cell to activate.

Finally once the T cells are activated the antibodies bind to the antigens on the surface of a cancer cell.(www.cancer.gov) Since that has happened the T cells then also detect cancer antigens inside the cancer cells. Once this has all happened the treatment begins to start. Many cancer vaccines do have side effects. Those side effects include inflammation at the site of injection, redness, pain, swelling, warming of the skin, itchiness, and sometimes a rash. You may get flu like symptoms such as fever, chills, weakness, dizziness, nausea, muscle ache, fatigue, and headaches. These symptoms do go away within a short amount of time and it just indicates that the vaccine is working and your body is making an immune response.

Cancer vaccines are not just given once. You are usually given with therapy over a long period of time. Studies have shown that if you do have surgery to remove a large tumor the cancer vaccines are more effective. I am so glad I could help you find a an effective cancer treatment. I wish you the best.

]]>

Related Essay Examples